Human Clinical Isolates of Pathogenic Fungi Are Host to Diverse Mycoviruses
Cormac M. Kinsella, Martin Deijs, H. M. Gittelbauer, Lia van der Hoek, Karin van Dijk
Abstract
Fungal pathogens of humans are a growing global health burden. Viruses of fungi may represent future therapeutic tools, but for many fungal pathogens there are no known viruses. Our study examined the viral content of diverse human-pathogenic fungi in a clinical biobank, identifying numerous viral genomes, including one lineage previously not known to infect fungi.
Topics & Concepts
MycovirusBiologyHuman viromeGenomeDNA sequencingHost (biology)VirologyGeneticsRNACryphonectriaNucleic acidVirusDNAGeneVirulenceRNA polymerasePlant and Fungal Interactions ResearchPlant Virus Research StudiesPlant Disease Management Techniques