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Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model

Jingru Qiu, Ye Chen, Jing Zhuo, Li Zhang, Jia Liu, Baozhu Wang, Deqing Sun, Shuyan Yu, Haiyan Lou

2022Neuropharmacology162 citationsDOI

Topics & Concepts

MitophagyNeuroinflammationMPTPMicrogliaNeurodegenerationInflammasomeNeuroprotectionPINK1DopaminergicPharmacologyChemistryNeuroscienceCell biologyBiologyInflammationImmunologyMedicineDopamineBiochemistryInternal medicineAutophagyApoptosisDiseasePomegranate: compositions and health benefitsSesame and Sesamin Research
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model | Litcius