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Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagy

Xiao-yun Ji, Dong Zheng, Rui Ni, Jinxi Wang, Jianqiang Shao, Zer Vue, Antentor Hinton, Long‐Sheng Song, Guo‐Chang Fan, Subrata Chakrabarti, Zhaoliang Su, Tianqing Peng

2022Acta Pharmacologica Sinica17 citationsDOIOpen Access PDF

Topics & Concepts

CalpainAutophagyGenetically modified mouseCardiomyopathyTransgeneDilated cardiomyopathyInternal medicineCardiac function curveEndocrinologyMyocyteHeart failureMedicineBiologyApoptosisBiochemistryEnzymeGeneCalpain Protease Function and RegulationAutophagy in Disease and TherapyRNA regulation and disease
Sustained over-expression of calpain-2 induces age-dependent dilated cardiomyopathy in mice through aberrant autophagy | Litcius