Hypoglycemic effect of a novel polysaccharide from<i>Lentinus edodes</i>on STZ-induced diabetic mice<i>via</i>metabolomics study and Nrf2/HO-1 pathway
Pin Gong, Xiaojuan Wang, Meng Liu, Mengrao Wang, Siyuan Wang, Yuxi Guo, Xiangna Chang, Wenjuan Yang, Xuefeng Chen, Fuxin Chen
Abstract
A novel polysaccharide, LNT-1, from Lentinus edodes may be a potential natural drug candidate for the prevention and treatment of diabetes by regulating the oxidative stress response.
Topics & Concepts
LentinusMetabolomicsDiabetes mellitusStreptozotocinPolysaccharidePharmacologyMetabolic pathwayOxidative stressChemistryBiochemistryMedicineBiologyMetabolismBioinformaticsFood scienceEndocrinologyMushroomFungal Biology and ApplicationsPhytochemicals and Antioxidant ActivitiesSeaweed-derived Bioactive Compounds