Deletion of calcineurin from astrocytes reproduces proteome signature of Alzheimer's disease and epilepsy and predisposes to seizures
Laura Tapella, Giulia Dematteis, Federico Alessandro Ruffinatti, Luisa Ponzoni, Fabio Fiordaliso, Alessandro Corbelli, Enrico Albanese, Beatrice Pistolato, Jessica Pagano, Elettra Barberis, Emílio Marengo, Claudia Balducci, Gianluigi Forloni, Chiara Verpelli, Carlo Sala, Carla Distasi, Mariaelvina Sala, Marcello Manfredi, Armando A. Genazzani, Dmitry Lim
Topics & Concepts
CalcineurinNeuroinflammationGliosisBiologyNeuroscienceEpilepsyProteomeCentral nervous systemNeurodegenerationAstrogliosisAstrocyteMedicineBioinformaticsImmunologyInternal medicineDiseaseInflammationTransplantationAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsSignaling Pathways in Disease