Activation and turnover of the plant immune signaling kinase BIK1: a fine balance
Márcia Gonçalves Dias, Faranak Soleimani, Jacqueline Monaghan
Abstract
Mechanisms to sense and respond to pathogens have evolved in all species. The plant immune pathway is initiated by the activation of transmembrane receptor kinases that trigger phosphorylation relays resulting in cellular reprogramming. BOTRYTIS-INDUCED KINASE 1 (BIK1) is a direct substrate of multiple immune receptors in Arabidopsis thaliana and is a central regulator of plant immunity. Here, we review how BIK1 activity and protein stability are regulated by a dynamic interplay between phosphorylation and ubiquitination.
Topics & Concepts
PhosphorylationArabidopsis thalianaCell biologyBiologyArabidopsisKinaseSignal transductionImmune systemPlant ImmunityImmune receptorBiochemistryReceptorGeneticsGeneMutantPlant-Microbe Interactions and ImmunityPlant Parasitism and ResistancePlant tissue culture and regeneration