Stabilization of the Pd–NHC framework with 1,2,4-triazol-5-ylidene ligands toward decomposition in alkaline media
Andrey Yu. Chernenko, Alexander V. Astakhov, Vadim V. Kutyrev, Evgeniy G. Gordeev, Julia V. Burykina, Mikhail E. Minyaev, Victor N. Khrustalev, Victor M. Chernyshev, Valentine P. Ananikov
Abstract
New NHC ligands containing a base-ionizable RNH substituent at the C3 atom of the 1,2,4-triazole ring provide superior stability of the Pd–NHC bond against cleavage in strong alkaline media.
Topics & Concepts
SubstituentChemistryRing (chemistry)DecompositionMedicinal chemistryCleavage (geology)TriazoleBond cleavageBase (topology)StereochemistryCatalysisOrganic chemistryMaterials scienceMathematicsMathematical analysisComposite materialFracture (geology)N-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis