Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution
Judith Díaz-García, Ana Gómez, Luís Alcalá, Elena Reigadas, Carlos Sánchez‐Carrillo, Ana Pérez‐Ayala, Elia Gómez‐García de la Pedrosa, Fernando González‐Romo, Paloma Merino Amador, María Soledad Cuétara, Coral García-Esteban, Inmaculada Quiles‐Melero, Nelly Daniela Zurita, María Muñoz‐Algarra, Isabel Sánchez‐Romero, María Teresa Durán-Valle, Aída Sánchez‐García, Eva Alcoceba, Patricia Muñóz, Pilar Escribano, Jesús Guinea
Abstract
= 39/43 isolates) that were found in four hospitals. Isolates harboring the G458S substitution clustered into another genotype found in a fifth hospital. C. parapsilosis genotypes demonstrating resistance to fluconazole have been spreading across hospitals in Madrid, Spain. Over the last 3 years, the frequency of isolation of such isolates and the number of hospitals affected is on the rise.