Multiregion exome sequencing of ovarian immature teratomas reveals 2N near-diploid genomes, paucity of somatic mutations, and extensive allelic imbalances shared across mature, immature, and disseminated components
Michael B. Heskett, John Z. Sanborn, Christopher Boniface, Benjamin Goode, Jocelyn Chapman, Karuna Garg, Joseph T. Rabban, Charles Zaloudek, Stephen C. Benz, Paul T. Spellman, David A. Solomon, Raymond J. Cho
Topics & Concepts
BiologyImmature teratomaLoss of heterozygosityOvarian TeratomaTeratomaGermlineSomatic cellGeneticsGerm cellOvaryPathologyGerm cell tumorsAlleleGeneMedicineChemotherapyOvarian cancer diagnosis and treatmentTesticular diseases and treatmentsRenal cell carcinoma treatment