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Resveratrol protects against doxorubicin-induced cardiotoxicity by attenuating ferroptosis through modulating the MAPK signaling pathway

Lu Chen, Xingang Sun, Zhen Wang, Miao Chen, Yuxian He, Han Zhang, Deheng Han, Liangrong Zheng

2023Toxicology and Applied Pharmacology58 citationsDOI

Topics & Concepts

MAPK/ERK pathwayCardiotoxicityPharmacologyp38 mitogen-activated protein kinasesKinaseDoxorubicinResveratrolProgrammed cell deathSignal transductionGlutathioneGPX4ChemistryCancer researchApoptosisCell biologyMedicineToxicityGlutathione peroxidaseBiologyBiochemistryChemotherapyInternal medicineEnzymeOrganic chemistryFerroptosis and cancer prognosisCircular RNAs in diseasesCancer, Lipids, and Metabolism
Resveratrol protects against doxorubicin-induced cardiotoxicity by attenuating ferroptosis through modulating the MAPK signaling pathway | Litcius