JNK/c-Jun-driven NLRP3 inflammasome activation in microglia contributed to retinal ganglion cells degeneration induced by indirect traumatic optic neuropathy
Xiaoqi Chu, Chun Wang, Zheng Wu, Liting Fan, Chunmei Tao, Jiaqi Lin, Shuang Chen, Yongzhong Lin, Yusong Ge
Topics & Concepts
InflammasomeMicrogliaNeuroinflammationRetinal degenerationNeurodegenerationRetinal ganglion cellNeuroscienceProgrammed cell deathCell biologyRetinalc-junRetinaBiologyMedicineImmunologyInflammationPathologyApoptosisBiochemistryDiseaseTranscription factorGeneTraumatic Brain Injury and Neurovascular DisturbancesTraumatic Ocular and Foreign Body InjuriesInflammasome and immune disorders