A NIR-I light-responsive superoxide radical generator with cancer cell membrane targeting ability for enhanced imaging-guided photodynamic therapy
Yingcui Bu, Tianren Xu, Xiaojiao Zhu, Jie Zhang, Lianke Wang, Zhipeng Yu, Jianhua Yu, Aidong Wang, Yupeng Tian, Hongping Zhou, Yi Xie
Abstract
experiments demonstrated that EBD-1 under 808 nm light successfully accomplished remarkable cancer ablation. This work will be beneficial for the design of novel photosensitizers for PDT-based theranostic systems.
Topics & Concepts
PhotosensitizerPhotodynamic therapyCancer imagingCancer cellViability assayCell membraneCancer researchMembraneCellChemistryBiophysicsCancerMedicinePhotochemistryBiologyBiochemistryInternal medicineOrganic chemistryNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials