Association of Parkinson Disease With Risk of Cardiovascular Disease and All-Cause Mortality
Joo‐Hyun Park, Do‐Hoon Kim, Yong Gyu Park, Do‐Young Kwon, Moonyoung Choi, Jin‐Hyung Jung, Kyungdo Han
Abstract
disease Parkinson disease stroke P arkinson disease (PD) is the second most common neurodegenerative disorder and affects 1% to 3% of people aged >65 years. As life expectancy increases, the prevalence and burden of PD increase worldwide. Although epidemiologic studies have consistently reported high PD-associated mortality, 2 the relationship between PD and cardiovascular diseases (CVDs), the leading cause of death, remains unclear. CVDs, such as myocardial infarction (MI), ischemic stroke, and congestive heart failure (CHF), are the most common medical conditions in older people. Although several studies have investigated the relationship between PD and CVD, the results remain controversial. Therefore, we conducted a nationwide, population-based cohort study to evaluate the risk of MI, ischemic stroke, CHF, and all-cause mortality in PD patients.