Statistical considerations of phase 3 umbrella trials allowing adding one treatment arm mid-trial
Yixin Ren, Xiaoyun Li, Cong Chen
Topics & Concepts
MedicineClinical trialType I and type II errorsResearch designControl (management)Phase (matter)Medical physicsClinical study designRisk analysis (engineering)Computer scienceStatisticsArtificial intelligencePathologyMathematicsOrganic chemistryChemistryStatistical Methods in Clinical TrialsOptimal Experimental Design MethodsBiosimilars and Bioanalytical Methods