Litcius/Paper detail

Low-N protein engineering with data-efficient deep learning

Surojit Biswas, Grigory Khimulya, Ethan C. Alley, Kevin M. Esvelt, George M. Church

2021Nature Methods418 citationsDOI

Topics & Concepts

In silicoDirected evolutionComputer scienceProtein engineeringComputational biologyThroughputSynthetic biologyMutantProcess (computing)Directed Molecular EvolutionField (mathematics)Representation (politics)Artificial intelligenceBiologyMachine learningGeneticsGenePoliticsBiochemistryOperating systemLawPolitical scienceTelecommunicationsMathematicsPure mathematicsEnzymeWirelessViral Infectious Diseases and Gene Expression in InsectsRNA and protein synthesis mechanismsProtein Structure and Dynamics