Litcius/Paper detail

Post-COVID-19 syndrome: persistent neuroimaging changes and symptoms 9 months after initial infection

Stephanie L. Grach, Ravindra Ganesh, Steven A. Messina, Ryan T. Hurt

2022BMJ Case Reports12 citationsDOIOpen Access PDF

Abstract

A previously healthy and active middle-aged woman acquired COVID-19 as an occupational exposure with subsequent persistent post-COVID-19 symptoms including headache, dyspnoea on exertion, chest pressure, tachycardia, anosmia, parosmia, persistent myalgia, vertigo, cognitive decline and fatigue. She presented to a tertiary medical centre for further evaluation after 9 months of persistent symptoms and had a largely unremarkable workup with the exception of a persistently elevated monocyte chemoattractant protein 1, blunted cardiovagal response and non-specific scattered areas of low-level hypometabolism at the bilateral frontal, left precuneus, occipital and parietal regions on PET scan.

Topics & Concepts

MedicinemyalgiaAnosmiaNeuroimagingNeurologyCognitive declineInternal medicineCardiologyPediatricsDementiaCoronavirus disease 2019 (COVID-19)DiseasePsychiatryInfectious disease (medical specialty)Long-Term Effects of COVID-19Fibromyalgia and Chronic Fatigue Syndrome ResearchNeuroinflammation and Neurodegeneration Mechanisms