In Praise of Basic Research as a Vehicle to Practical Applications: Palladium‐Catalyzed Coupling to Form Carbon‐Nitrogen Bonds
Stephen L. Buchwald, John F. Hartwig
Abstract
Two groups' research initiated to address two very different questions on problems of basic chemical research led, after much effort on catalyst development and studies of reaction mechanism, to the discovery and development of the coupling of amines with aryl halides in a practical fashion.
Topics & Concepts
ChemistryPraisePalladiumCoupling (piping)CatalysisNitrogenCarbon fibersPolymer chemistryOrganic chemistryPsychologyComposite numberMetallurgyComposite materialMaterials sciencePsychotherapistCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsChemical Synthesis and Analysis