A Phase I dose-escalation, pharmacokinetics and food-effect study of oral donafenib in patients with advanced solid tumours
Xiaoyu Li, Meng Qiu, Shengjun Wang, Hong Zhu, Feng Bi, Li Zheng
Topics & Concepts
PharmacokineticsMaximum tolerated doseMedicinePharmacologyOncologyInternal medicineHedgehog Signaling Pathway StudiesMelanoma and MAPK PathwaysDrug Transport and Resistance Mechanisms