Influence of natural convection on gold nanorods-assisted photothermal treatment of bladder cancer in mice
Ean Hin Ooi, Viktor Popov, Massimo Alfano, Jason K. K. Cheong
Abstract
Natural convection inside the bladder can be beneficial but also detrimental to GNR-assisted PTT depending on the level of heating. At low levels of heating due to low GNR volume fraction and/or laser power, flow inside the bladder may dissipate heat from the targeted tissue; making the treatment ineffective. At high levels of heating due to high GNR volume fraction and/or laser power, cooling may prevent excessive thermal damage to surrounding tissues.
Topics & Concepts
Natural convectionPhotothermal therapyNanorodMaterials scienceBladder cancerCancerConvectionMedicineUrologyInternal medicineNanotechnologyMechanicsPhysicsNanoplatforms for cancer theranosticsBladder and Urothelial Cancer TreatmentsPhotoacoustic and Ultrasonic Imaging