The anticancer application of half-sandwich iridium(<scp>iii</scp>) ferrocene-thiosemicarbazide Schiff base complexes
Xicheng Liu, Ao Lv, Pei Zhang, Jiaying Chang, Ruixiao Dong, Mengxian Liu, Jiayi Liu, Xiaoqing Huang, Xiang‐Ai Yuan, Zhe Liu
Abstract
toxicity assays confirmed that these complexes showed better anti-migration ability and less toxicity in comparison to cisplatin. Thus, these complexes provide a new strategy for the design of non-platinum organometallic anticancer drugs.
Topics & Concepts
ChemistryFerroceneIridiumSchiff basePlatinumIn vivoCisplatinFlow cytometryStereochemistryLigand (biochemistry)ApoptosisCombinatorial chemistryBiochemistryMolecular biologyReceptorElectrochemistryBiologyChemotherapyPhysical chemistryCatalysisGeneticsElectrodeBiotechnologyFerrocene Chemistry and ApplicationsMetal complexes synthesis and propertiesDendrimers and Hyperbranched Polymers