Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects
Edmond F. O’Donnell, Hyo Sang Jang, Daniel F. Liefwalker, Nancy I. Kerkvliet, Siva K. Kolluri
Topics & Concepts
Aryl hydrocarbon receptorTranscription factorCancer researchBiologyBasic helix-loop-helixFas ligandSignal transductionDownregulation and upregulationCancer cellCell biologyAryl hydrocarbon receptor nuclear translocatorApoptosisCancerProgrammed cell deathDNA-binding proteinGeneticsGeneToxic Organic Pollutants ImpactEffects and risks of endocrine disrupting chemicalsCarcinogens and Genotoxicity Assessment