Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate
Amanda L. Graboski, Mark E. Kowalewski, Joshua B. Simpson, Xufeng Cao, Minggui Ha, Jianan Zhang, William G. Walton, Daniel P. Flaherty, Matthew R. Redinbo
Topics & Concepts
ChemistryIndole testTryptophanaseBiochemistryMetabolismToxicityTryptophanEnzymeSulfatePharmacologyMicrobiologyBiologyAmino acidOrganic chemistryGut microbiota and healthDialysis and Renal Disease ManagementBipolar Disorder and Treatment