Quantification of SARS-CoV-2 spike and nucleocapsid proteins using isotope dilution tandem mass spectrometry
Carrie L. Pierce-Ruiz, Wanda I. Santana, William J.H. Sutton, David A. Fischler, Hans C. Cooper, Lidoshka R. Marc, John R. Barr, Tracie L. Williams
Topics & Concepts
Mass spectrometryIsotope dilutionChromatographyTandem mass spectrometryChemistryQuantitative proteomicsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Protein subunitSpike (software development)CoronavirusLabel-free quantificationProteomicsVirologyBiologyCoronavirus disease 2019 (COVID-19)BiochemistryMedicineGeneDiseasePathologyEconomicsManagementInfectious disease (medical specialty)Influenza Virus Research StudiesSARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing