Hearing impairment-associated KARS mutations lead to defects in aminoacylation of both cytoplasmic and mitochondrial tRNALys
Yong Wang, Jing-Bo Zhou, Qiyu Zeng, Siqi Wu, Mei-Qin Xue, Pengfei Fang, En‐Duo Wang, Xiao-Long Zhou
Topics & Concepts
AminoacylationBiologyAminoacyl tRNA synthetaseMitochondrionTransfer RNACytosolMutantMutationGeneticsTranslation (biology)BiochemistryEnzymeRNAGeneMessenger RNARNA and protein synthesis mechanismsRNA modifications and cancerRNA Research and Splicing