A high-throughput assay for the quantification of intact Insulin-like Growth Factor I in human serum using online SPE-LC-HRMS
Gilles Coppieters, Péter Judák, Nicolas Van Haecke, Pieter Van Renterghem, Peter Van Eenoo, Koen Deventer
Topics & Concepts
ChromatographyDetection limitIon suppression in liquid chromatography–mass spectrometryChemistryImmunoassayInsulin-like growth factorSample preparationProtein precipitationGrowth hormoneRepeatabilityMass spectrometryGrowth factorLiquid chromatography–mass spectrometryHormoneMedicineReceptorBiochemistryImmunologyAntibodyGrowth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders