Catalytic alkane C–H functionalization by carbene insertion into unactivated C(sp<sup>3</sup>)–H bonds
Yongzhen Pan, Yeming Wang, Swastik Karmakar, Paramasivam Sivaguru, Zhaohong Liu
Abstract
This review summarizes the developments in the C–H functionalization of saturated hydrocarbons (C n H 2 n +2 and C n H 2 n ) through catalytic carbene insertion into their C–H bonds dated up to February 2024, based on the categories of the types of carbenes.
Topics & Concepts
CarbeneChemistrySurface modificationCatalysisAlkaneMedicinal chemistryStereochemistryPolymer chemistryOrganic chemistryPhysical chemistryCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry