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Pd-Catalyzed Triple-Fold C(sp<sup>2</sup>)–H Activation with Enaminones and Alkenes for Pyrrole Synthesis via Hydrogen Evolution

Leiqing Fu, Yunyun Liu, Jie‐Ping Wan

2021Organic Letters72 citationsDOI

Abstract

)-H bond in enaminone, has been activated to provide various pyrroles. The interesting evolution of hydrogen gas from the reactions has been observed by a hydrogen detector.

Topics & Concepts

ChemistryCatalysisPyrroleTriple bondAnnulationHydrogen bondHydrogenMedicinal chemistryCombinatorial chemistryStereochemistryOrganic chemistryMoleculeDouble bondSynthesis and Characterization of PyrrolesCatalytic C–H Functionalization MethodsOrganic Chemistry Cycloaddition Reactions
Pd-Catalyzed Triple-Fold C(sp<sup>2</sup>)–H Activation with Enaminones and Alkenes for Pyrrole Synthesis via Hydrogen Evolution | Litcius