Catalyst-controlled regiodivergent Friedel–Crafts reactions of 1-naphthols with 2,3-dioxopyrrolidines: synthesis of polycyclic 2-pyrrolidinones
Si-Kai Liu, Pei‐Hsuan Chien, Bo‐Wei Huang, Jeng‐Liang Han
Abstract
The catalyst-controlled regiodivergent Friedel–Crafts reactions of 1-naphthols with 2,3-dioxopyrrolidines have been developed.
Topics & Concepts
Friedel–Crafts reactionChemistrySelectivityCatalysisLewis acids and basesPyrrolidinonesOrganic chemistryBrønsted–Lowry acid–base theoryAxial and Atropisomeric Chirality SynthesisSynthesis of Indole DerivativesAsymmetric Synthesis and Catalysis