Assessment of Aging-Related Function Variations of P-gp Transporter in Old-Elderly Chinese CHF Patients Based on Modeling and Simulation
Cheng Cui, Yuchen Qu, Jie En Valerie Sia, Zhu Zhu, Yang Wang, Jing Ling, Haiyan Li, Yan Jiang, Jie Pan, Dongyang Liu
Topics & Concepts
Physiologically based pharmacokinetic modellingMedicineRenal functionPharmacokineticsDigoxinDosingPharmacologyPopulationInternal medicineCreatinineHeart failureEnvironmental healthDrug Transport and Resistance MechanismsDiabetes Treatment and ManagementHeart Failure Treatment and Management