An easy-to-perform evaluation of steric properties of Lewis acids
Ludwig Zapf, Melanie Riethmann, Steffen A. Föhrenbacher, Maik Finze, Udo Radius
Abstract
An easy-to-perform approach to assess and quantify steric properties of Lewis acids is reported. The novel LAB-Rep model (Lewis acid/base repulsion model) is introduced, which judges steric repulsion in Lewis acid/base pairs.
Topics & Concepts
Steric effectsLewis acids and basesChemistryCombinatorial chemistryComputer scienceComputational chemistryStereochemistryOrganic chemistryCatalysisOrganoboron and organosilicon chemistryCrystallography and molecular interactionsChemical Synthesis and Reactions