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A copper metal–organic framework-based electrochemical sensor for identification of glutathione in pharmaceutical samples

Reshma Kaimal, Aashutosh Dube, Abdullah Al Souwaileh, Jerry J. Wu, Sambandam Anandan

2023The Analyst35 citationsDOI

Abstract

at the detection limit (LOD; 0.1 ± 0.005 μM) and a large dynamic range of 0.1-20 μM. Boosting the conductivity and surface area enhances electron transport and promotes redox processes. The constructed sensors were also adequately selective against interference from other contaminants in a similar potential window. Furthermore, the Cu-MOF heterostructure has outstanding selectivity, long-term stability, and repeatability, and the given sensors have demonstrated their capacity to detect GSH with high accuracy (recovery range = 98.2-100.8%) in pharmaceutical samples.

Topics & Concepts

Materials scienceScanning electron microscopeElectrochemical gas sensorDetection limitCopperHeterojunctionMetal-organic frameworkElectrodeRedoxAnalytical Chemistry (journal)Transmission electron microscopyElectrochemistryChemical engineeringChemistryNanotechnologyOptoelectronicsChromatographyMetallurgyOrganic chemistryPhysical chemistryAdsorptionComposite materialEngineeringSulfur Compounds in BiologyAdvanced Nanomaterials in CatalysisMetal-Organic Frameworks: Synthesis and Applications
A copper metal–organic framework-based electrochemical sensor for identification of glutathione in pharmaceutical samples | Litcius