Design, synthesis and biological evaluation of anthranilamide derivatives as potent SMO inhibitors
Dezhong Ji, Wanwan Zhang, Yungen Xu, Jing‐Jing Zhang
Topics & Concepts
SmoothenedChemistryPhthalazineHedgehogHedgehog signaling pathwayIC50Inhibitory postsynaptic potentialReporter geneBiochemistryStereochemistrySignal transductionIn vitroGeneGene expressionBiologyOrganic chemistryNeuroscienceHedgehog Signaling Pathway StudiesOral and gingival health researchOcular Disorders and Treatments