Performance of the T2Candida Panel for the Diagnosis of Intra-abdominal Candidiasis
Frédéric Lamoth, Cornelius J. Clancy, Frédéric Tissot, Kevin M Squires, Philippe Eggimann, Ursula Flückiger, Martin Siegemund, Christina Orasch, Stefan Zimmerli, Thierry Calandra, Oscar Marchetti, Minh Nguyen, Pierre–Yves Bochud
Abstract
Performance of T2Candida for detecting intra-abdominal candidiasis (IAC) was assessed in 48 high-risk patients. T2Candida sensitivity/specificity and positive/negative predictive values were 33%/93% and 71%/74%, respectively. IAC was present in 100% of cases with concordant positive T2Candida/1,3-beta-d-glucan and absent in 90% of concordant negative results. Combination T2Candida/1,3-beta-d-glucan may help guide treatment decisions.
Topics & Concepts
MedicineInvasive candidiasisPredictive valueInternal medicinePositive predicative valueGastroenterologyDermatologyFluconazoleAntifungalAntifungal resistance and susceptibilityAntibiotic Use and ResistancePneumonia and Respiratory Infections