Tetramethylpyrazine inhibits the inflammatory response by downregulating the TNFR1/IκB-α/NF-κB p65 pathway after spinal cord injury
Gang Liu, Luyao Huo, Bowen Deng, Shengyuan Jiang, Yi Zhao, Yanjun Mo, Huizhong Bai, Lin Xu, Chuanyu Hu, Xiaohong Mu
Topics & Concepts
KEGGTetramethylpyrazinePharmacologyTumor necrosis factor alphaSuperoxide dismutaseNF-κBIκBαChemistryNeuroprotectionSignal transductionMalondialdehydeReactive oxygen speciesOxidative stressCell biologyBiologyImmunologyBiochemistryGene expressionMedicinePathologyGeneAlternative medicineTranscriptomeSpinal Cord Injury ResearchPeroxisome Proliferator-Activated ReceptorsNeuroinflammation and Neurodegeneration Mechanisms