Colorimetric Test for Fast Detection of SARS-CoV-2 in Nasal and Throat Swabs
Bartolomeo Della Ventura, Michele Cennamo, Antonio Minopoli, Raffaele Campanile, Sergio Bolletti Censi, Daniela Terracciano, Giuseppe Portella, Raffaele Velotta
Abstract
) of a real-time PCR (gold standard for detecting the presence of viruses) finding that the colorimetric method is able to detect very low viral load with a detection limit approaching that of the real-time PCR. Since the method is sensitive to the infecting viral particle rather than to its RNA, the achievements reported here open a new perspective not only in the context of the current and possible future pandemics, but also in microbiology, as the biosensor proves itself to be a powerful though simple tool for measuring the viral particle concentration.
Topics & Concepts
Colloidal goldContext (archaeology)VirologyThroatGold standard (test)BiosensorDetection limitSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Particle (ecology)Coronavirus disease 2019 (COVID-19)NanotechnologyCoronavirusNanoparticleChemistryChromatographyBiologyMaterials scienceMedicineInternal medicineDiseaseInfectious disease (medical specialty)PathologyPaleontologyEcologyAnatomySARS-CoV-2 detection and testingBiosensors and Analytical DetectionSARS-CoV-2 and COVID-19 Research