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Overcoming acquired resistance to PD-1 inhibitor with the addition of metformin in small cell lung cancer (SCLC)

Yeseul Kim, Elena Vagia, Pedro Viveiros, Cyra Y. Kang, Ju Young Lee, Gahyun Gim, Sukjoo Cho, Horyun Choi, Leeseul Kim, In-Ae Park, Jaeyoun Choi, Young Kwang Chae

2020Cancer Immunology Immunotherapy43 citationsDOIOpen Access PDF

Topics & Concepts

MetforminNivolumabMedicineCytotoxic T cellImmunotherapyTumor-infiltrating lymphocytesLung cancerCancer researchImmune systemCD8Immune checkpointCancerCombination therapyTumor hypoxiaInternal medicineOncologyImmunologyInsulinBiologyIn vitroRadiation therapyBiochemistryLung Cancer Research StudiesNeuroendocrine Tumor Research AdvancesCancer Immunotherapy and Biomarkers
Overcoming acquired resistance to PD-1 inhibitor with the addition of metformin in small cell lung cancer (SCLC) | Litcius