Looking back, moving forward: protein corona of lipid nanoparticles
Yue Gao, Yeqi Huang, Chuanyu Ren, Peiwen Chou, Chuanbin Wu, Xin Pan, Guilan Quan, Zhengwei Huang
Abstract
fate of LNPs was explored. The mechanisms underlying PC formation, including the adsorption theory and alteration theory, were introduced to delve into the formation process. Subsequently, the existing experimental outcomes were synthesized to offer insights into the research and application facets of PC, and it was concluded that the manipulation of PC held substantial promise in the realm of targeted delivery.
Topics & Concepts
Corona (planetary geology)NanoparticleMaterials scienceNanotechnologyCorona dischargeEngineeringPhysicsElectrical engineeringAstrobiologyVoltageVenusNanoparticle-Based Drug DeliveryProtein Interaction Studies and Fluorescence AnalysisLipid Membrane Structure and Behavior