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Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice

Krystyna Mazan-Mamczarz, Dimitrios Tsitsipatis, Bennett G. Childs, Angelica E. Carr, Carla Rocha Dos Santos, Carlos Anerillas, Brigette Romero, Jordan Gregg, Charnae' Henry-Smith, Ada N. Okereke, Marc Michel, Rachel Munk, Jennifer L. Martindale, Yulan Piao, Jinshui Fan, Maria O. Hernandez, Noémi Kedei, Michael L Viacheslavov, Madeline Wong, О. В. Федорова, Mona Batish, Supriyo De, Darren J. Baker, Myriam Gorospe, Allison B. Herman

2025Nature Aging23 citationsDOIOpen Access PDF

Topics & Concepts

TranscriptomeCellMedicineInternal medicineCardiologyBiologyGene expressionGeneGeneticsBiochemistrySingle-cell and spatial transcriptomicsAtherosclerosis and Cardiovascular DiseasesNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Single-cell and spatial transcriptomics map senescent vascular cells in arterial remodeling during atherosclerosis in mice | Litcius