Computational design of constitutively active cGAS
Quinton M. Dowling, Hannah E. Volkman, Elizabeth Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K. Bera, Banumathi Sankaran, Max Johnson, Matthew J. Bick, Alex Kang, Daniel B. Stetson, Neil P. King
Topics & Concepts
Stimulator of interferon genesInnate immune systemBiologyCell biologyDNAInterferonEnzymeMutantReceptorBiochemistryChemistryGeneGeneticsinterferon and immune responsesImmune Response and InflammationRNA regulation and disease