Glucosylation endows nanoparticles with TLR4 agonist capability to trigger macrophage polarization and augment antitumor immunity
Li Liu, Shengxiang Fu, Wencheng Zhu, Zhongyuan Cai, Yingzi Cao, Yubing Huang, Li Yang, Xiaomin Fu, Rongrong Jin, Chunchao Xia, Yunjiao Zhang, Su Lui, Qiyong Gong, Bin Song, Longping Wen, James M. Anderson, Hua Ai
Topics & Concepts
Macrophage polarizationTLR4Immune systemIn vivoCancer immunotherapyInnate immune systemMaterials scienceIn vitroMacrophageImmunotherapyChemistryBiologyImmunologyBiochemistryBiotechnologyImmune cells in cancerImmunotherapy and Immune ResponsesImmune Response and Inflammation