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Asymmetric isochalcogenourea-catalysed (4 + 2)-cycloadditions of <i>ortho</i>-quinone methides and allenoates

Anna Scheucher, Christoph Groß, Magdalena Piringer, Johanna Novacek, Armin R. Ofial, Mario Waser

2024Organic & Biomolecular Chemistry12 citationsDOIOpen Access PDF

Abstract

Chiral isochalcogenoureas catalyse the asymmetric (4 + 2)-cycloaddition of various allenoates with ortho -quinone methides giving access to chromane derivatives with high selectivities.

Topics & Concepts

QuinoneChemistryOrganic chemistryMedicinal chemistrySynthesis of Indole DerivativesChemical Synthesis and ReactionsCarbohydrate Chemistry and Synthesis
Asymmetric isochalcogenourea-catalysed (4 + 2)-cycloadditions of <i>ortho</i>-quinone methides and allenoates | Litcius