Litcius/Paper detail

The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center

João P. L. Coelho, Matthew C. J. Yip, Keely Oltion, Jack Taunton, Sichen Shao

2024Nature Chemical Biology21 citationsDOIOpen Access PDF

Topics & Concepts

RibosomeStop codonRelease factorTranslation (biology)Ribosomal RNAGeneticsBiologyEukaryotic RibosomeChemistryCell biologyMessenger RNAGeneRNARNA and protein synthesis mechanismsRNA modifications and cancerPeptidase Inhibition and Analysis