Identification of a 3-β-homoalanine conjugate of brusatol with reduced toxicity in mice
Nicky Hwang, Yonggang Pei, Jason A. Clement, Erle S. Robertson, Yanming Du
Topics & Concepts
ChemistryConjugateIn vivoToxicityMicrosomePharmacologyIn vitroBioavailabilityBiochemistryOrganic chemistryBiologyBiotechnologyMedicineMathematicsMathematical analysisPhytochemical compounds biological activitiesNatural product bioactivities and synthesisMicrobial Natural Products and Biosynthesis