Astaxanthin alleviates lipopolysaccharide-induced acute lung injury by suppressing ferroptosis
Xue Dong, Dandan Li, Zhiyao Fang, Chenyang Zhang, Jia Wang, Xianyao Wan
Abstract
suppressing ferroptosis, and could also reduce unstable iron accumulation by inhibiting NCOA4-mediated ferritin phagocytosis from mitigating lipid peroxidation and ferroptosis in lung epithelial cells.
Topics & Concepts
AstaxanthinLipopolysaccharideMechanism (biology)ChemistryPharmacologyLungMedicineImmunologyBiochemistryCarotenoidInternal medicinePhysicsQuantum mechanicsFerroptosis and cancer prognosisCancer-related molecular mechanisms researchCircular RNAs in diseases