Progressive endothelial cell damage in correlation with sepsis severity. Defibrotide as a contender
Sara Fernández, Marta Palomo, Patricia Molina, Maribel Díaz‐Ricart, Ginés Escolar, Adrián Téllez, Ferran Seguí, Helena Ventosa, Sergi Torramadé‐Moix, Montserrat Rovira, Enric Carreras, Josep M. Nicolás, Pedro Castro
Topics & Concepts
SepsisVon Willebrand factorMedicineEndotheliumSeptic shockEndothelial dysfunctionImmunologyInflammationEndothelial stem cellProinflammatory cytokineDefibrotidePathophysiologyCell adhesion moleculeThrombogenicityPlateletEndothelial activationInternal medicineBiologyIn vitroHematopoietic stem cell transplantationBiochemistryTransplantationSepsis Diagnosis and TreatmentTrauma, Hemostasis, Coagulopathy, ResuscitationImmune Response and Inflammation