Physiologically based Pharmacokinetic Model Validated to Enable Predictions Of Multiple Drugs in a Long-acting Drug-combination Nano-Particles (DcNP): Confirmation with 3 HIV Drugs, Lopinavir, Ritonavir, and Tenofovir in DcNP Products
Simone Perazzolo, Danny D. Shen, Ariel M. Scott, Rodney J. Y. Ho
Topics & Concepts
LopinavirPhysiologically based pharmacokinetic modellingPharmacologyPharmacokineticsRitonavirDrugDosingMedicineDrug interactionDrug deliveryChemistryHuman immunodeficiency virus (HIV)VirologyViral loadAntiretroviral therapyOrganic chemistryHIV Research and TreatmentEpilepsy research and treatmentAdvanced Drug Delivery Systems