Novel nitrogen mustard-artemisinin hybrids with potent anti-leukemia action through DNA damage and activation of GPx
Tianzhi Dai, Lan Lin, Huan Chen, Wenyu Lu, Xuelian Yang, Yang Li, Ying Liu, Jichun Cui, Dequn Sun
Topics & Concepts
ChemistryLeukemiaDNA damageDoxorubicinNitrogen mustardPharmacologyCell growthCancer researchLymphoblastCell cycleCell cultureBiochemistryApoptosisDNAImmunologyBiologyChemotherapyCyclophosphamideGeneticsCancer therapeutics and mechanismsSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological Evaluation