Litcius/Paper detail

Novel nitrogen mustard-artemisinin hybrids with potent anti-leukemia action through DNA damage and activation of GPx

Tianzhi Dai, Lan Lin, Huan Chen, Wenyu Lu, Xuelian Yang, Yang Li, Ying Liu, Jichun Cui, Dequn Sun

2022European Journal of Medicinal Chemistry14 citationsDOI

Topics & Concepts

ChemistryLeukemiaDNA damageDoxorubicinNitrogen mustardPharmacologyCell growthCancer researchLymphoblastCell cycleCell cultureBiochemistryApoptosisDNAImmunologyBiologyChemotherapyCyclophosphamideGeneticsCancer therapeutics and mechanismsSynthesis and Characterization of Heterocyclic CompoundsSynthesis and Biological Evaluation