Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells
Yi Zhang, Kathleen E. McGrath, Edward Ayoub, Paul D. Kingsley, Hongbo Yu, Kate Fegan, Kelly A. McGlynn, Sarah Rudzinskas, James Palis, Archibald S. Perkins
Abstract
mouse model will be useful to deconvolute the complexity of hematopoiesis as it unfolds in the embryo and functions postnatally.
Topics & Concepts
HaematopoiesisBiologyStem cellYolk sacHematopoietic stem cellHemangioblastMyeloidImmunologyCell biologyProgenitor cellBone marrowSpleenEmbryoZebrafish Biomedical Research ApplicationsImmune cells in cancerHematopoietic Stem Cell Transplantation