Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
Bahadır Bülbül, Kai Ding, Chang‐Guo Zhan, Gamze Çiftçi, Kemal Yelekçi, Merve Gürboğa, Özlem Bingöl Özakpınar, Esra Aydemir, Deniz Baybağ, Fikrettin Şahi̇n, Necla Kulabaş, Sinem Helvacıoğlu, Mohammad Charehsaz, Esra Tatar, Süheyla Özbey, İlkay Küçükgüzel
Topics & Concepts
HeLaCytotoxicityMTT assayChemistryCancer cellAngiogenesisIn vitroPharmacologyCancerCytotoxic T cellK562 cellsProstaglandin E2BiochemistryCancer researchBiologyMedicineInternal medicineSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Biological Evaluation