T follicular helper and B cell crosstalk in tertiary lymphoid structures and cancer immunotherapy
Soizic Garaud, Marie‐Caroline Dieu‐Nosjean, Karen Willard‐Gallo
Abstract
Tumor-infiltrating lymphocytes (TILs) are critical in the elimination of cancer cells, a concept highlighted by recent advances in cancer immunotherapy. Significant evidence reveals that their organization in tertiary lymphoid structures together with specific subpopulation composition/balances stimulates cellular crosstalk and anti-tumor immunity in patients.
Topics & Concepts
CrosstalkImmunotherapyCancer immunotherapyTumor-infiltrating lymphocytesImmunologyCancer researchImmunityMedicineBiologyImmune systemPhysicsOpticsCancer Immunotherapy and BiomarkersImmune Cell Function and InteractionT-cell and B-cell Immunology